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GENES, ABL
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DeCS
Descriptor
English
:
Genes, abl
Descriptor
Spanish
:
Genes abl
Descriptor
Portuguese
:
Genes abl
Synonyms
English
:
abl Genes
c-abl Genes
v-abl Genes
Tree Number:
G14.340.024.340.383.500.791.100
Definition
English
:
Retrovirus-associated
DNA
sequences (abl) originally isolated from the
Abelson murine leukemia virus
(Ab-MuLV). The proto-oncogene abl (c-abl)
codes
for a protein that is a member of the
tyrosine
kinase
family
. The human c-abl gene is located at 9q34.1 on the long
arm
of chromosome 9. It is activated by translocation to bcr on chromosome 22 in chronic myelogenous
leukemia.
Indexing Annotation
English
:
abl stands for "ABelson Leukemia"
See Related
English
:
Fusion Proteins, bcr-abl
Oncogene Proteins v-abl
Proto-Oncogene Proteins c-abl
History Note
English
:
91
Allowable Qualifiers
English
:
drug effects
ethics
genetics
immunology
physiology
radiation effects
Record Number:
28952
Unique Identifier:
D016313
Occurrence in VHL
:
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